Methyl 3-(4-chlorophenyl)-1-methyl-1,2,3,3a,4,11c-hexahydrobenzo[f]chromeno[4,3-b]pyrrole-3a-carboxylate
نویسندگان
چکیده
منابع مشابه
Mixed Cocaine Agonist/Antagonist Properties of ( )-Methyl 4 -(4-Chlorophenyl)-1-methylpiperidine-3 -carboxylate, a Piperidine-Based Analog of Cocaine
The present study investigated the pharmacological properties of a piperidine-based novel cocaine analog, namely, ( )-methyl 4 (4-chlorophenyl)-1-methylpiperidine-3 -carboxylic acid [( )CPCA]. Like cocaine, ( )-CPCA inhibited rat synaptosomal dopamine and norepinephrine uptake with high affinity, but was 33-fold less potent than cocaine in inhibiting serotonin uptake. Like cocaine, ( )-CPCA is ...
متن کاملMethyl N-(4-chlorophenyl)succinamate
In the structure of the title compound {systematic name: methyl 3-[(4-chloro-phen-yl)amino-carbon-yl]propionate}, C(11)H(12)ClNO(3), the conformations of the N-H and C=O bonds in the amide fragment are trans to each other and the conformations of the amide O atom and the carbonyl O atom of the ester fragment are also trans to the H atoms attached to the adjacent C atoms. Mol-ecules are linked i...
متن کاملMethyl 3-(4-methoxyphenyl)-1-methyl-1,2,3,3a,4,11b-hexahydrobenzo[f]chromeno[4,3-b]pyrrole-3a-carboxylate
In the title compound, C(25)H(25)NO(4), the pyrrolidine ring exhibits an envelope conformation and the tetra-hydro-pyran ring exhibits a half-chair conformation. The crystal structure is stabilized by inter-molecular C-H⋯π inter-actions.
متن کاملMethyl 3-(4-bromophenyl)-1-methyl-1,2,3,3a,4,9b-hexahydrobenzo[f]chromeno[4,3-b]pyrrole-3a-carboxylate
In the title compound, C(24)H(22)BrNO(3), the dihydro-pyran ring adopts a half-chair conformation, whereas the pyrrolidine ring is in an envelope conformation. The bromo-phenyl group is oriented at an angle of 66.44 (4)° with respect to the naphthalene ring system. In the crystal structure, mol-ecules are linked into centrosymmetric dimers by C-H⋯π inter-actions and the dimers are connected via...
متن کاملMethyl 3-(4-fluorophenyl)-1-methyl-1,2,3,3a,4,9b-hexahydrochromeno[4,3-b]pyrrole-3a-carboxylate
In the title compound, C(20)H(20)FNO(3), the pyrrolidine and benzopyran rings adopt half chair and twisted half chair conformations, respectively. The carboxyl-ate group is almost perpendicular to the pyran ring [89.4 (1)°].
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2010
ISSN: 1600-5368
DOI: 10.1107/s1600536810005465